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Chicken STING Mediates Activation of the IFN Gene Independently of the RIG-I Gene
Results indicated that chSTING is an important regulator of chicken innate immune signaling and might be involved in the MDA5 signaling pathway in chicken cells, and these results help with understanding the biological role of STING in innate immunity during evolution. Expand
Characterization and determination of holin protein of Streptococcus suis bacteriophage SMP in heterologous host
The results suggest that HolSMP is the holin protein of phage SMP and a two-step lysis system exists in SMP. Expand
Muscovy duck retinoic acid-induced gene I (MdRIG-I) functions in innate immunity against H9N2 avian influenza viruses (AIV) infections.
It is found that RIG-I expression in brain, spleen, lung and bursa were up-regulated in ducks challenged with H9N2 avian influenza virus, whose six internal genes were closely related to the H7N9 and H10N8 AIV. Expand
Combined Antibacterial Activity of Phage Lytic Proteins Holin and Lysin from Streptococcus suis Bacteriophage SMP
HolSMP was identified as a promising antibacterial agent which was able to extend the spectrum of LySMP and combined use of holin and lysin could be a candidate strategy for resolution of drug resistance. Expand
Application of a Bacteriophage Lysin To Disrupt Biofilms Formed by the Animal Pathogen Streptococcus suis†
The results suggest that bacteriophage lysin could form part of an effective strategy to treat S. suis infections and represents a new class of antibiofilm agents. Expand
Development of a rapid and simultaneous immunochromatographic assay for the determination of zearalenone and fumonisin B1 in corn, wheat and feedstuff samples
Abstract A rapid and simultaneous immunochromatographic assay for the detection of zearalenone and fumonisin B1 was developed and optimized. Specific monoclonal antibodies against zearalenone orExpand
An immunomagnetic-bead-based enzyme-linked immunosorbent assay for sensitive quantification of fumonisin B1
Abstract A sensitive enzyme-linked immunosorbent assay (ELISA) based on immunomagnetic beads (IMB-ELISA) was established using a magnetic-bead signal-enrichment system. The immunomagnetic beads wereExpand
A Phage Lysin Fused to a Cell-Penetrating Peptide Kills Intracellular Methicillin-Resistant Staphylococcus aureus in Keratinocytes and Has Potential as a Treatment for Skin Infections in Mice
CPTat-JDlys was able to combat MRSA-induced murine skin infections and, consequently, expedite the healing of cutaneous abscesses and suggest that the novel antimicrobial CPP- JDlys may be a worthwhile candidate as a treatment for skin and skin structure infections caused by MRSA. Expand
Chicken TBK1 interacts with STING and is involved in IFN-β signaling regulation.
It is concluded that chTBK1 is involved in chSTING-triggered IFN-β signaling in chicken cells through the generation of various ch TBK1 mutant forms and through endogenous Co-IP and LC-MS/MS. Expand
Two myeloid differentiation factor 88 (MyD88) isoforms identified in ducks.
The results verify the existence of a MyD 88-dependent signaling pathway in ducks and contribute to understanding the potential role of MyD88s in the innate immune response. Expand