Sort by:

• Highly Influential Citations
• Citations
• Acceleration
• Velocity
• Recency

Learn More

3,4-methylenedioxymethamphetamine (MDMA) administration to rats decreases brain tissue serotonin but not serotonin transporter protein and glial fibrillary acidic protein.

• Xiaoying Wang, Michael Heinrich Baumann, Heng Li Xu, Richard B. Rothman
• Synapse
• 2004

UNLABELLED Previous experiments conducted in this laboratory showed that administration of high-dose D-fenfluramine (D-FEN) and p-chloroamphetamine (PCA) decreased 5-HT transporter (SERT) binding and… (More)

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.

• Heng Li Xu, Wenjian Yang, +24 authors Jun J. Yang
• Journal of the National Cancer Institute
• 2013

BACKGROUND Acute lymphoblastic leukemia (ALL) is the most common cancer in children and the incidence of ALL varies by ethnicity. Although accumulating evidence indicates inherited predisposition to… (More)

[Antibiotic resistance and plasmid profiles of Vibrio isolates from cultured Sparus sarba].

• Jingbao Li, Junming Yie, +4 authors Heng Li Xu
• Wei sheng wu xue bao = Acta microbiologica Sinica
• 1999

A total of 51 potential pathogenic vibrios were isolated from moribund silver seabream Sparus sarba, which were collected from local fish farms of Hong Kong. All the isolates were classified and… (More)

(+/-)-3,4-Methylenedioxymethamphetamine administration to rats does not decrease levels of the serotonin transporter protein or alter its distribution between endosomes and the plasma membrane.

• Xiaoying Wang, Michael Heinrich Baumann, Heng Li Xu, Marisela Morales, Richard B. Rothman
• The Journal of pharmacology and experimental…
• 2005

We showed that the serotonin (5-HT) neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) reduces brain tissue 5-HT, decreases expression of 5-HT transporter (SERT) protein, and increases expression of glial… (More)

Antinociceptive and hypothermic effects of Salvinorin A are abolished in a novel strain of kappa-opioid receptor-1 knockout mice.

• Michael A. Ansonoff, Jiwen Zhang, +8 authors John E. Pintar
• The Journal of pharmacology and experimental…
• 2006

Salvia divinorum is a natural occurring hallucinogen that is traditionally used by the Mazatec Indians of central Mexico. The diterpene salvinorin A was identified as an active component of S.… (More)

Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans.

• Subramaniam Ananthan, Hollis S Kezar, +9 authors Richard B. Rothman
• Journal of medicinal chemistry
• 1999

A series of pyrido- and pyrimidomorphinans (6a-h and 7a-g) were synthesized from naltrexone and evaluated for binding and biological activity at the opioid receptors. The unsubstituted pyridine 6a… (More)

Overexpression of AtDOF4.7, an Arabidopsis DOF family transcription factor, induces floral organ abscission deficiency in Arabidopsis.

• Pengcheng Wei, Feng Tan, +6 authors Xue-chen Wang
• Plant physiology
• 2010

After flower pollination, a programmed process called abscission occurs in which unwanted floral organs are actively shed from the main plant body. We found that a member of the DOF (for DNA binding… (More)

Identification of (3R)-7-hydroxy-N-((1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)- 3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl)-1,2,3,4-tetrahydro- 3-isoquinolinecarboxamide as a novel potent and…

• James B. Thomas, Robert N. Atkinson, +10 authors F Ivy Carroll
• Journal of medicinal chemistry
• 2003

(3R)-7-Hydroxy-N-((1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) was identified as a potent and selective… (More)

Identification of a GBR12935 homolog, LR1111, which is over 4,000-fold selective for the dopamine transporter, relative to serotonin and norepinephrine transporters.

• Richard B. Rothman, Brandon Lewis, +7 authors Agu Pert
• Synapse
• 1993

The di-substituted piperazines, GBR12909 (1-[2-[bis(4-fluorophenyl)-methoxy]ethyl]-4-[3- phenylpropyl]piperazine) and GBR12935 (1-[2-(diphenyl-methoxy)-ethyl]-4-(3-phenylpropyl)piperazine), are… (More)

Opioid peptide receptor studies. 17. Attenuation of chronic morphine effects after antisense oligodeoxynucleotide knock-down of RGS9 protein in cells expressing the cloned Mu opioid receptor.

• Heng Li Xu, Xiaoying Wang, Jun Wang, Richard B. Rothman
• Synapse
• 2004

RGS proteins are a recently described class of regulators that influence G-protein-mediated signaling pathways. We have shown previously that chronic morphine results in functional uncoupling of the… (More)

• ‹
• 1
• 2
• 3
• 4
• 5
• ›