Heng-Chuan Kan

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In this work, a mixed Eulerian–Lagrangian algorithm, called ELAFINT (Eulerian Lagrangian algorithm for interface tracking) is developed further and applied to compute flows with solid–fluid and fluid–fluid interfaces. The method is capable of handling fluid flows in the presence of both irregularly shaped solid boundaries and moving boundaries on a fixed(More)
The rheological properties of a leukocyte significantly affect its biological and mechanical characteristics. To date, existing physical models of leukocyte are not capable of quantitatively explaining the wide range of deformation and recovery behaviors observed in experiment. However, a compound drop model has gained some success. In the present work, we(More)
A three-layer Newtonian model is investigated using a combined Eulerian-Lagrangian computational method to describe the dynamic behaviour of leukocytes. The model, composed of a cell membrane (outer layer), cytoplasm (middle layer) and nucleus (inner layer), can better describe the recovery characteristics because large viscosity and capillarity differences(More)
We demonstrate a rapid antibiotic susceptibility test (AST) based on the changes in dielectrophoretic (DEP) behaviors related to the β-lactam-induced elongation of Gram-negative bacteria (GNB) on a quadruple electrode array (QEA). The minimum inhibitory concentration (MIC) can be determined within 2 h by observing the changes in the positive-DEP frequency(More)
In the present study, THUBioGrid, an experimental distributed computing application for bioinformatics (BioGrid) is proposed. THUBioGrid incorporates directory services (data and software), grid computing methods (security, authentication, data transport and remote jobs), and gene sequence/genomic data processing methods. It uses Java CoG Kit plus(More)
In this paper, we report on implementing an experimental distributed computing application for bioinformatics consisting of basic high-performance computing environments (Grid and PC Cluster systems), multiple interfaces at user portals that provide useful graphical interfaces to enable biologists who are not IT specialists to benefit directly from the use(More)
Biological data exists all over the world as various Web services, which provide biologists with much useful information. However, heterogeneous data formats present a technical hurdle for biologists to fully take advantage of the information. It needs some power tools to handle this issue. The grid technology could help common biology tools with high(More)
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