Heng Chi

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The genus of Flavivirus contains important human pathogens , including dengue (DENV), yellow fever (YFV), West Nile (WNV), Japanese encephalitis (JEV), and tick-borne encephalitis (TBEV) viruses, which cause a number of serious human diseases throughout the world (Pierson TC, 2013). Zika virus (ZIKV) is also an arthropod-borne flavivirus, which was(More)
Cerebral ischemia is a major health crisis throughout the world, and the currently available thrombolytic therapy is unsatisfactory. Cell death following cerebral ischemia is mediated by a complex pathophysiological interaction of various mechanisms. During an ischemic insult, not only neurons but all of the components of the neurovascular unit, such as(More)
SUMMARY Nonlinear elastic materials are of great engineering interest, but challenging to model with standard finite elements. The challenges arise because nonlinear elastic materials are characterized by non-convex stored-energy functions as a result of their ability to undergo large reversible deformations, are incompressible or nearly incompressible, and(More)
The recent explosive outbreak of Zika virus (ZIKV) infection has been reported in South and Central America and the Caribbean. Neonatal microcephaly associated with ZIKV infection has already caused a public health emergency of international concern. No specific vaccines or drugs are currently available to treat ZIKV infection. The ZIKV helicase, which(More)
BACKGROUND HIV envelope glycoprotein gp120 is the main protein that causes HIVassociated sensory neuropathy. However, the underlying mechanisms of gp120-induced neurotoxicity are still unclear. There are lack effective treatments for relieving HIV-related neuropathic symptoms caused by gp120-induced neurotoxicity. METHODS In the present study, tyrosine(More)
Pseudomonas fluorescens is a common bacterial pathogen to a wide range of aquaculture animals including various species of fish. In this study, we employed proteomic analysis and identified filamentous hemagglutinin (FHA) as an iron-responsive protein secreted by TSS, a pathogenic P. fluorescens isolate. In vitro study showed that compared to the wild type,(More)
Fundamentals of Parallel Programming (COMP 322) is a required course for all Computer Science majors at Rice University. It introduces students to several basic concepts of parallel programming and parallel algorithms and follows a " pedagogic approach that exposes students to intellectual challenges in parallel software without enmeshing them in jargon and(More)
  • Heng Chi, Oscar Lopez-Pamies, Glaucio, H Paulino, B Glaucio
  • 2015
This paper presents a new variational principle in finite elastostatics applicable to arbitrary elastic solids that may contain constitutively rigid spatial domains (e.g., rigid inclusions). The basic idea consists in describing the con-stitutive rigid behavior of a given spatial domain as a set of kinematic constraints over the boundary of the domain. From(More)
Fundamentals of Parallel Programming (COMP 322) is a required course for all Computer Science majors at Rice University. It introduces students to several basic concepts of parallel programming and parallel algorithms and follows a "pedagogic approach that exposes students to intellectual challenges in parallel software without enmeshing them in jargon and(More)
The T-box transcription factor T-bet is expressed in a number of hematopoietic cell types in mammals and plays an essential role in the lineage determination of Th1 T-helper cells and is considered as an essential feature for both innate and adaptive immune responses in higher vertebrates. In the present study, we have identified and characterized the(More)
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