Hendrik Brune

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Medulloblastomas (MBs), the most frequent malignant brain tumors of childhood, presumably originate from cerebellar neural precursor cells. An essential fetal mitogen involved in the pathogenesis of different embryonal tumors is insulin-like growth factor II (IGF-II). We screened human MB biopsies of the classic (CMB) and desmoplastic (DMB) variants for(More)
Connexin45 (Cx45) is known to be expressed in the retina, but its functional analysis was problematic because general deletion of Cx45 coding DNA resulted in cardiovascular defects and embryonic lethality at embryonic day 10.5. We generated mice with neuron-directed deletion of Cx45 and concomitant activation of the enhanced green fluorescent protein(More)
Mit einem Workshop hat der Berufsverband der Schmerztherapeuten in Deutschland e.V. (BVSD) am 02.02.2007 in Berlin seine bundespolitische Arbeit aufgenommen. Vor führenden Vertretern der Standespolitik entwickelte BVSD-Präsident Dr. Reinhard Thoma die Ziele des im Dezember neu gegründeten Bundesverbandes. Wichtig, so Thoma, sei es vor allem, die vielfach(More)
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