Hemanshu H. Parikh

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Purpose. To develop and validate a rapid method for determining thedissociation constants with which pharmaceutical candidates and drugsbind to serum albumin and to α1-acid glycoprotein with the goal ofdeducing the extent of binding. Methods. The quenching of the intrinsic tryptophan fluorescence ofserum albumin and α1-acid glycoprotein was monitored(More)
BACKGROUND The Kolmogorov-Smirnov test is a valid statistical test for comparing distributions that has been recommended for flow cytometric histogram analysis. However, this test is frequently found to be too sensitive for flow cytometric histogram comparisons. Here, a parametric alternative to the Kolmogorov-Smirnov test is proposed that is based on(More)
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