Helmut Saule

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Long-chain polyunsaturated fatty acids (LCP) are considered conditionally essential nutrients for the infant born prematurely, and attempts are being made to match fatty acid profiles of formula and breast fed infants. In this double-blind, randomized study we investigated the effects of a formula enriched with both n-6 and n-3 LCP on plasma fatty acid(More)
This is the report of two independent families in which a balanced maternal translocation led to trisomy 12 p in one of each their offspring. Evaluation of 21 further case reports indicates that this is a phenotypically well defined syndrome which leads to severe developmental retardation. It can be recognized by a characteristic combination of craniofacial(More)
Two different ventilation techniques were compared in a seven-centre, randomised trial with 181 preterm infants up to and including 32 completed weeks gestational age, who needed mechanical ventilation because of lung disease of any type. Technique A used a constant rate (60 cycles/min), inspiratory time (IT) (0.33s) and inspiratory: expiratory ratio (I:E)(More)
On the basis of two observations, the clinical symptoms for acquired knee extension contracture in childhood was presented. A progressive fibrosis of the vastus intermedius of the musculus quadriceps femoris develops as a result of multiple injections into the ventral thigh musculature. This method of application should, therefore, be avoided and an(More)
A newborn boy was admitted with a congenital rubella infection. Seven years previously his mother had been vaccinated against rubella; 3 years previously rubella immunity had been confirmed. Therefore, intrauterine transmission must have occurred after maternal reinfection during pregnancy. Prenatal diagnosis of rubella embryopathy with serological methods(More)
In the treatment of acute diarrheal disease in infants reinstituting the normal intestinal homeostasis is of primary importance. Prompt rehydration should be accomplished with a well balanced glucose electrolyte solution by parenteral or oral route. From a diet, given after rehydration, lactose and long chain fatty acids must be eliminated. Antibiotics,(More)
  • H Saule
  • 1976
In the present uncontrolled study the effectiveness and tolerance of aminophylline suppositories were assayed in 79 children of varying age, based on clinical and chemical laboratory findings. Results as well as specific dosage problems are discussed. Special emphasis is laid on the advantages provided by the application of suppositories in the treatment of(More)
  • H Saule
  • 1978
13 preterms and 10 term-babies were fed with two commercially available amino acid solutions (mother milk-adapted and requirement-adapted) under the same test conditions. Method and results were compared and discussed. None of the solutions showed amino acid imbalances 4 hours after discontinuation of continuous infusion over 20 hours. This applies also to(More)