Helmut Gekeler

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OBJECTIVES The rapid and accurate diagnosis of heart failure in primary care is a major unmet clinical need. We evaluated the additional use of B-type natriuretic peptide (BNP) levels. DESIGN A randomized controlled trial. SETTING Twenty-nine primary care physicians in Switzerland and Germany coordinated by the University Hospital Basel, Switzerland. (More)
Natriuretic peptides reflect cardiac stress and may therefore be useful in the management of patients with valvular heart disease. Data regarding these biomarkers in organic mitral regurgitation (MR) are sparse. In this study, 144 patients with moderate or severe organic MR were prospectively enrolled in an observational, multicenter study to analyze the(More)
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