Helgi Kolk

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The present study aimed at assessing the counts and species distribution of intestinal lactobacilli and exploring if the data are associated with BMI and blood glucose level in healthy adults and elderly persons. The BMI (P < 0·01), the level of fasting blood glucose (P < 0·001) and the total counts of lactobacilli (P < 0·01 by bacteriology; P < 0·001 by(More)
AIM To assess the prevalence of physical, depressive, and cognitive disorders in the elderly population in Estonia. METHODS The prevalence of various common morbidities was determined by a questionnaire sent to 200 general practitioners (GP). GPs were asked to collect data, use medical records, and interview five randomly selected patients (a total of(More)
Safety of the probiotic Lactobacillus plantarum strain Tensia (DSM 21380) was tested in vitro, in semihard Edam-type cheese, in an animal model and after consumption of the probiotic cheese in double-blind randomized placebo-controlled human intervention studies with different age groups. The susceptibility of L. plantarum Tensia to 8 antibiotics, and the(More)
BACKGROUND Some dominant bacterial divisions of the intestines have been linked to metabolic diseases such as overweight and diabetes. OBJECTIVE A pilot study aimed to evaluate the relations between the culturable intestinal bacteria with body mass index (BMI) and some principal cellular and metabolic markers of blood in people older than 65. DESIGN(More)
The higher counts or particular groups (Firmicutes/Bacteroidetes) of intestinal microbiota are related to host metabolic reactions, supporting a balance of human ecosystem. We further explored whether intestinal lactobacilli were associated with some principal cellular and metabolic markers of blood in 38 healthy >65-year-old persons. The questionnaire,(More)
OBJECTIVE To find a possible relation between the dynamics of antibiotic resistance of Helicobacter pylori isolates and the consumption of antibiotics during the last several years in Estonia. METHODS Helicobacter pylori isolates were collected from the gastric mucosa of patients with peptic ulcer (153) and gastritis (68) and isolated on the Columbia Agar(More)
The prevalence of metronidazole and clarithromycin resistance of Helicobacter pylori strains under different growth conditions (microaerophilic or anaerobic preincubation) was tested in 56 patients suffering from gastritis and peptic ulcer. vacA subtypes were detected in 46 H. pylori strains and were subsequently compared with the antibiotic resistance(More)
BACKGROUND Dyspepsia is a common syndrome and provides primary care physicians with a significant workload. To optimize the management of dyspepsia, several guidelines have been developed. OBJECTIVE The aim of this study was to determine the incidence of upper gastrointestinal diseases and their relationship to Helicobacter pylori infection in dyspeptic(More)
OBJECTIVE To assess the prevalence of diagnoses of cardiovascular disorders among the elderly in family practice. DESIGN Cross-sectional study. SETTING Estonia, population aged 65 years or older (206,915 persons). SUBJECTS 811 elderly persons selected randomly from the lists of family practitioners. MAIN OUTCOME MEASURES Prevalence of hypertension,(More)
BACKGROUND Guidelines for management of peptic ulcer patients after the treatment are largely directed to detection of H. pylori infection using only non-invasive tests. We compared the diagnostic value of non-invasive and endoscopy based H. pylori tests in a late post-treatment setting. METHODS Altogether 34 patients with dyspeptic complaints were(More)