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Identification of serum proteins discriminating colorectal cancer patients and healthy controls using surface-enhanced laser desorption ionisation-time of flight mass spectrometry.

• Judith Y. M. N. Engwegen, Helgi H Helgason, +4 authors Jos H. Beijnen
• World journal of gastroenterology
• 2006

AIM To detect the new serum biomarkers for colorectal cancer (CRC) by serum protein profiling with surface-enhanced laser desorption ionisation--time of flight mass spectrometry (SELDI-TOF MS). … (More)

Brain metastases in patients with renal cell cancer receiving new targeted treatment.

• Helgi H Helgason, Henk A Mallo, +4 authors E. van Boven
• Journal of clinical oncology : official journal…
• 2008

Phase II and pharmacological study of oral docetaxel plus cyclosporin A in anthracycline pre-treated metastatic breast cancer.

• Helgi H Helgason, Stijn L W Koolen, +7 authors Jan H. M. Schellens
• Current clinical pharmacology
• 2014

INTRODUCTION Previously, we demonstrated that oral docetaxel plus the P-glycoprotein (Pgp; ABCB1) inhibitor cyclosporin A (CsA) is safe and results in adequate exposure to docetaxel. This phase II… (More)

Identification of serum proteins as prognostic and predictive markers of colorectal cancer using surface enhanced laser desorption ionization-time of flight mass spectrometry.

• Helgi H Helgason, Judith YMN Engwegen, +5 authors Jan H. M. Schellens
• Oncology reports
• 2010

Colorectal cancer (CRC) is the second most common cause of cancer related death. Prognosis is highly dependent on stage at diagnosis making early detection mandatory. This study aimed to identify… (More)

Consensus-based evaluation of clinical significance and management of anticancer drug interactions.

• Frank G. A. Jansman, An K L Reyners, +9 authors Jacobus R. B. J. Brouwers
• Clinical therapeutics
• 2011

BACKGROUND Anticancer drug interactions can affect the efficacy and toxicity of anticancer treatment and that of the interacting drugs. However, information on the significance, prevention, and… (More)

Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary.

• Hugo M. Horlings, Ryan K van Laar, +10 authors Daphne de Jong
• Journal of clinical oncology : official journal…
• 2008

PURPOSE Patients with adenocarcinoma of unknown primary origin (ACUP) constitute approximately 4% of all malignancies. For effective treatment of these patients, it is considered optimal to identify… (More)

[Testicular cancer in Iceland 2000-2009: Incidence and survival].

• Andri Wilberg Orrason, Bjarni Agnar Agnarsson, Gudmundur Geirsson, Helgi H Helgason, Tómas Gudbjartsson
• Laeknabladid
• 2011

INTRODUCTION Survival of patients with testicular germ cell tumours has improved in recent years, mainly due to new modes of chemotherapy. We analyzed incidence, staging and survival of patients… (More)

Serum proteomics and disease-specific biomarkers of patients with advanced gastric cancer.

• Helgi H Helgason, Judith Y. M. N. Engwegen, +4 authors Jan H. M. Schellens
• Oncology letters
• 2010

Gastric cancer is a commonly diagnosed solid tumor which is associated with a dismal prognosis making early diagnosis essential. Thus, this study aimed to identify novel biomarkers in gastric cancer.… (More)

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