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Denervation suppresses gastric tumorigenesis
Surgical or pharmacologic interruption of muscarinic innervation to the stomach suppresses gastric tumor growth in mice and humans. Treating Cancer by Getting on Its Nerves The nervous system plays aExpand
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PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery
Summary Roux-en-Y gastric bypass (RYGB) is a weight-reduction procedure resulting in rapid resolution of type 2 diabetes (T2D). The role of pancreatic islet function in this restoration ofExpand
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Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action
BackgroundRecently, the US FDA has approved “vagal blocking therapy or vBLoc® therapy” as a new treatment for obesity. The aim of the present study was to study the mechanism-of-action of “VBLOC” inExpand
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Steady-state energy balance in animal models of obesity and weight loss
Abstract Objective: We wanted to exam the steady-state energy balance by using high-fat diet-induced obese (DIO) rats and mice as models for positive energy balance, and gastric bypassed (GB) ratsExpand
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Eating Behavior and Glucagon-Like Peptide-1-Producing Cells in Interposed Ileum and Pancreatic Islets in Rats Subjected to Ileal Interposition Associated with Sleeve Gastrectomy
BackgroundIleal interposition–sleeve gastrectomy (II–SG) has been developed as a metabolic surgery based on the hindgut hypothesis. The aim of the present study was to test this hypothesis byExpand
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New Approaches for Weight Loss: Experiments Using Animal Models.
The number of people who are overweight and obese are continuously increasing both in the adult and adolescent populations. Coinciding with this is the increased prevalence of health problems such asExpand
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Tu1980 Altered Eating Behavior by Subdiaphragmatic Truncal Vagus Nerve Stimulation in Rats
Background: Stress is a major contributing factor to the pathophysiology of IBS and accelerates colonic transit and increases in defecation. The parasympathetic vagal and pelvic nerves regulateExpand
Okabe S., Kodama Y., Cao H., Johannessen H., Zhao C. M., Wang T. C., Takahashi R, Chen D. Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model.Expand