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Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor.

• Vladimir V Kalinichenko, Michael L Major, +8 authors Robert H. Costa
• Genes & development
• 2004

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. Here, we provide evidence that the Forkhead Box (Fox) m1b (Foxm1b or Foxm1) transcription factor is essential for… (More)

The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer.

• Yuichi Yoshida, I-Ching Wang, Helena M Yoder, Nicholas O. Davidson, Robert H. Costa
• Gastroenterology
• 2007

BACKGROUND & AIMS In this study, we used Forkhead Box m1b (Foxm1b) transgenic mice and conditional Foxm1 knock-out mice to examine the role of Foxm1 in colon cancer development and proliferation. … (More)

The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature.

• Il-man Kim, Sneha Ramakrishna, Galina A. Gusarova, Helena M Yoder, Robert H. Costa, Vladimir V Kalinichenko
• The Journal of biological chemistry
• 2005

Transgenic and gene knock-out studies demonstrated that the mouse Forkhead Box m1 (Foxm1 or Foxm1b) transcription factor (previously called HFH-11B, Trident, Win, or MPP2) is essential for hepatocyte… (More)

The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis.

• Katherine Krupczak-Hollis, Xinhe Wang, +7 authors Robert H. Costa
• Developmental biology
• 2004

Conditional deletion of the mouse Forkhead Box (Fox) m1b targeted allele in adult hepatocytes (Foxm1, previously called HFH-11B, Trident, Win, or MPP2) demonstrated that the Foxm1b transcription… (More)

The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer.

• Il-man Kim, Timothy J Ackerson, +8 authors Vladimir V Kalinichenko
• Cancer research
• 2006

The proliferation-specific Forkhead Box m1 (Foxm1 or Foxm1b) transcription factor (previously called HFH-11B, Trident, Win, or MPP2) regulates expression of cell cycle genes essential for progression… (More)

Ubiquitous expression of the forkhead box M1B transgene accelerates proliferation of distinct pulmonary cell types following lung injury.

• Vladimir V Kalinichenko, Galina A. Gusarova, +5 authors Robert H. Costa
• The Journal of biological chemistry
• 2003

The delayed early transcription factor Forkhead Box M1B (FoxM1B) is expressed in proliferating cells, but its expression is extinguished in cells undergoing terminal differentiation. Liver… (More)

Foxf1 haploinsufficiency reduces Notch-2 signaling during mouse lung development.

• Vladimir V Kalinichenko, Galina A. Gusarova, +6 authors Robert H. Costa
• American journal of physiology. Lung cellular and…
• 2004

The forkhead box (Fox) f1 transcription factor is expressed in the mouse splanchnic (visceral) mesoderm, which contributes to development of the liver, gallbladder, lung, and intestinal tract.… (More)

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