Helena L Mannix

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BACKGROUND Off-label and unlicensed (OLUL) prescribing has been prevalent in pediatric practice. Using data from a prospective cohort study of adverse drug reactions (ADRs) among pediatric inpatients, we aimed to test the hypothesis that OLUL status is a risk factor for ADRs. METHODS A nested case?control study was conducted within a prospective cohort(More)
BACKGROUND Adverse drug reactions (ADRs) are an important cause of harm in children. Current data are incomplete due to methodological differences between studies: only half of all studies provide drug data, incidence rates vary (0.6% to 16.8%) and very few studies provide data on causality, severity and risk factors of pediatric ADRs. We aimed to determine(More)
1 Department of Women’s and Children’s Health, University of Liverpool, First Floor, Liverpool Women's Hospital, Crown Street, Liverpool, L8 7SS, UK 2 Department of Biostatistics, University of Liverpool, Shelley's Cottage, Brownlow Street, Liverpool, L69 3GS, UK 3 Research and Development, Alder Hey Children’s NHS Foundation Trust, Eaton Road, Liverpool,(More)
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