Helena Cannon

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Two studies were undertaken to verify the presence of lowered platelet monoamine oxidase activity in chronic schizophrenia. In the first study, a retrospective chart analysis, the mean platelet activity of patients with chronic schizophrenia (7.73+/-0.64 nmol of benzylaldehyde product per 10(8) platelets per hour [S.E.M.]) differed significantly from that(More)
Little is known about patients' experience of, and knowledge about adjuvant endocrine therapy. A European survey was carried out to explore this knowledge gap. The 547 post-menopausal women with early breast cancer, from 9 European countries, completed a questionnaire about their experience and knowledge of their therapy. Forty one percent of women surveyed(More)
OBJECTIVE The objective was 2-fold: (1) to evaluate the feasibility and value of developing a Pharmacy and Therapeutics (P&T) subcommittee aimed at scientifically evaluating complementary and alternative medicine (CAM) products for an integrated managed care organization (IMCO) and (2) to assess provider acceptance and usefulness of a CAM guide. METHODS(More)
BACKGROUND Few patients with migraine syndrome receive treatment with preventive medication regimens, and some of these patients fail to gain adequate migraine relief. Botulinum toxin has been suggested to be effective in the treatment of migraine for a select population. An integrated health system created a medical policy and a supporting preauthorization(More)
OBJECTIVE To assess the effects of benefit design change (BDC) on medication adherence and persistence (including switch in therapy), drug costs, and total healthcare costs. STUDY DESIGN A retrospective study was performed using administrative claims data from an integrated healthcare system between January 2001 and December 2002. METHODS Continuously(More)
BACKGROUND Hereditary hemochromatosis (HH) is a genetic disorder resulting in increased accumulation of dietary iron. It is associated with various clinical complications such as liver cirrhosis and diabetes. The aim of this study was to explore patients' experiences of living with HH, the diagnosis process, and phlebotomy treatment. STUDY DESIGN AND(More)
A total of 670 adults living or working with leprosy patients, were examined for a BCG vaccination scar, and skin-tested with four new tuberculins. Based on the results 513 were vaccinated, 65 with Bacille de Calmette et Guérin (BCG) alone, 66 with BCG plus killed Mycobacterium vaccae and 382 with killed M. vaccae alone. Skin-testing was repeated 2-3 years(More)
The long-term outcome of chronic schizophrenia has classically been accepted to be pessimistic, most often leading to a terminal demented state. An examination of recent literature that has followed schizophrenic patients into the involutional years is not so convincing. The few studies that so report upon elderly schizophrenics demonstrate substantially(More)
BACKGROUND Respiratory syncytial virus (RSV) is the leading cause of upper and lower respiratory tract infections in infants and young children. Most children are exposed to the virus before they are 2 years old and experience such symptoms as cough, fever, and irritability. In a select population of infants, the virus can cause hypoxemia and(More)
BACKGROUND Chronic obstructive pulmonary disease (COPD), a systemic inflammatory condition, is costly and often devastating to patient quality of life. COPD is also greatly underdiagnosed and often inappropriately treated. A managed care organization therefore evaluated whether a systemwide COPD clinical program within its organization may be appropriate.(More)