Helen Sikorski

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1. Methods for preparing small amounts of Type I meningococcal polysaccharide which are electrophoretically homogeneous and contain only traces of other immunologically reactive material are given. 2. These polysaccharides are very poor antigens in man but in a small number of instances definite amounts of precipitin and protective antibody were formed. 3.(More)
The demonstration by Francis and Tillett (1) and others (2-5) that the typespecific polysaccharides of pneumococci are antigenic in man and induce the production of antibodies in humans which protect mice against subsequent injection of virulent organisms, has led to numerous attempts to use these purified polysaccharides in active immunization (4, 6).(More)
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