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A human Cds 1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage
Checkpoints maintain the order and fidelity of the eukaryotic cell cycle, and defects in checkpoints contribute to genetic instability and cancer. Much of our current understanding of checkpoints… Expand
Abstract 4708: Investigating triple negative breast cancer phenotypic heterogeneity of human and patient-derived xenograft samples using imaging mass cytometry
Tumors are highly heterogeneous populations of cells, and measures of intratumoral heterogeneity (ITH) and diversity correlate with worse prognosis in many cancers, including breast cancer. Emerging… Expand
, Saeko Serine 379 Signaling through Autophosphorylation of Regulation of Chk 2 Ubiquitination and
Purification and biochemical characterization of non-myristoylated recombinant pp 6 Oc-src kinase
To obtain sufficient material for the biochemical and biophysical study of pp60-carc, we have utilized a recombinant pp6oc-8rc baculovirus lacking the myristoylation site at codon 2. On infection of… Expand