Helen M. Kent

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COPI mediates retrograde trafficking from the Golgi to the endoplasmic reticulum (ER) and within the Golgi stack, sorting transmembrane proteins bearing C-terminal KKxx or KxKxx motifs. The structure of KxKxx motifs bound to the N-terminal WD-repeat domain of β'-COP identifies electrostatic contacts between the motif and complementary patches at the center(More)
VAMP7 is involved in the fusion of late endocytic compartments with other membranes. One possible mechanism of VAMP7 delivery to these late compartments is via the AP3 trafficking adaptor. We show that the linker of the δ-adaptin subunit of AP3 binds the VAMP7 longin domain and determines the structure of their complex. Mutation of residues on both partners(More)
  • A Laser Applications, Ezekiel Dr Shaoul, H Kent, Lloyd A Casleton, Hackel, Salvatore R Balsamo +6 others
  • 2009
127 Magnetic octopole and scalar spin-spin interactions have been observed in 12 by 11 using laser-molecular beam techniques for precise measurement (one part in 10 l) of the hyperfine spectrum on the P(13) 43-0 line. The values of the coupling strengths obtained from fitting the spectrum to 5 kHz are as follows: for the electric quadrupole, t S s-2. 72 ±(More)
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