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PURPOSE To assess efficacy of an intervention delivered by an interactive, computer-controlled telephone system to improve individuals' diets. DESIGN Randomized controlled trial. SETTING Large multispecialty group practice. SUBJECTS Two hundred ninety-eight adults who were both sedentary and had suboptimal diet quality. INTERVENTION Weekly(More)
The purpose of this investigation was to determine whether there is an effect of age and the presence of predisposing risk factors on the pattern of bone resorption in men with spinal osteoporosis. We present iliac bone histomorphometric data after in vivo double tetracycline labeling in 21 men aged 34–74 with significant spinal osteoporosis as evidenced by(More)
OBJECTIVES: To document the outcomes of a telephone coverage system and identify patient characteristics that may predict these outcomes. DESIGN: Telephone survey. SETTING: An academic outpatient medical practice that has a physician telephone coverage service. PATIENTS: All patients (483) who called during the 3-week study period to speak to a physician(More)
BACKGROUND We evaluated a multifaceted preventive nutrition intervention to improve dietary habits among adult primary care patients. METHODS We randomized six group practices in a managed care organization. Participants completed baseline and 3-month follow-up surveys. The intervention comprised (1) mailed personalized dietary recommendations and(More)
BACKGROUND United States public health goals call for increased physician counseling about diet and exercise, but many medical schools lack adequate curriculum on these topics. At Harvard Medical School, second-year students take a preventive medicine and nutrition (PMN) course. This study evaluated the impact of this innovative curriculum on students'(More)
The Dietary Approaches to Stop Hypertension (DASH) and DASH-sodium trials were controlled feeding dietary trials that lowered blood pressure in the absence of weight loss. The beneficial aspect of DASH appears to be the low saturated fat content (< 7%). Sodium restriction added additional blood pressure lowering to the low saturated fat DASH diet. Sodium(More)
BACKGROUND Nutrition education has presented an ongoing challenge to medical educators. In the 2007-2008 academic year, Harvard Medical School replaced its dedicated Preventive Medicine and Nutrition course with an integrated curriculum. The objective of the current study was to assess the effect of the curriculum change on medical student attitudes and(More)
BACKGROUND We report process data on the feasibility of delivering a clinical preventive nutrition intervention that was effective in increasing participants' consumption of fruits and vegetables. We also examine relationships between process variables and study outcomes. METHODS We randomly assigned six practice sites in a managed care organization to a(More)
To the Editor: In the Case Record, Delichatsios et al. (May 12 issue)1 discussed the development of abrupt adult-onset psychosis and delusional thinking in a 37-year-old woman with Hashimoto’s thyroiditis and a clinically significant weight loss. A unifying diagnosis of celiac disease was made. During a 3-month hospitalization, the patient did not eat(More)
The effect of recombinant human tumour necrotic factor-alpha (TNF-alpha) on the intratumour and whole-body distributions of 90Y-labelled C110 anticarcinoembryonic antigen (CEA) monoclonal antibody (MAb) was studied using nude mice bearing two different tumours. The nude mice were injected subcutaneously with the CEA-positive LS174T colorectal cancer(More)