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Selective attention is critical for controlling the input to mental processes. Attentional mechanisms act not only to select relevant stimuli but also to exclude irrelevant stimuli. There is evidence that we can actively ignore irrelevant information. We measured neural activity relating to successfully ignoring distracters (using preview search) and found(More)
We measured behavioural performance and fMRI activity whilst old and young adults performed a temporal segmentation task ('preview search'). Being able to select parts of the visual world to be attended or ignored is a critical visual skill. Both old and young adults were able to improve their performance on a difficult search task when some of the(More)
Ninety-eight consecutive patients with myelodysplastic syndrome were randomized to a treated or a control group, both receiving conventional supportive therapy. The treated group were given 13-cis-retinoic acid 20 mg/d if marrow blasts were less than or equal to 5% or cytosine arabinoside 10 mg/d subcutaneously on 6 d/week if marrow blasts were 6-30%, to(More)
Observers can use spatial scale information flexibly depending on categorisation task and on their prior sensitisation. Here, we explore whether attentional modulation of spatial frequency processing at early stages of visual analysis may be responsible. In three experiments, we find that observers' perception of spatial frequency (SF) band-limited scene(More)
We present several wavelet transform algorithms and their applications in astronomical image processing (restoration, object detection , compression, etc.). Extensive literature exists on the wavelet transform and its application (Chui 1992; Daubechies 1992; Meyer 1989). A discrete wavelet transform approach can be obtained from multiresolution analysis(More)
OBJECTIVES To estimate the incidence, clinical characteristics and risk factors for culture-confirmed invasive bacterial infections in England. DESIGN Prospective, observational, study of all children with positive blood and/or cerebrospinal fluid (CSF) culture over a 3-year period (2009-2011). SETTING All five hospitals within a geographically defined(More)
This paper reports quantitative results from a pilot study in primary care (PC) undertaken from 2004-2007. The intervention programme, derived from movement psychotherapy was termed " Learning groups: the bodymind approach, " and emphasized a verbal and non-verbal integrated model, awareness of the interrelationship between body and mind and a self-managing(More)
BACKGROUND Early antiretroviral therapy (ART) and virological suppression can affect evolving antibody responses to HIV infection. We aimed to assess frequency and predictors of seronegativity in infants starting early ART. METHODS We compared HIV antibody results between two of three treatment groups of the Children with HIV Early Antiretroviral Therapy(More)
Pandemic influenza A (H1N1) virus infection was first identified in March 2009 1 ; more than 3000 deaths have been reported worldwide , 2 with highest complication rates in those with preexisting medical conditions. 3 Patients with sickle cell disease (SCD) are thought to be at increased risk of complications, although there are limited data supporting(More)