Helen E D Burchett

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OBJECTIVE To evaluate the effectiveness of youth development in reducing teenage pregnancy, substance use, and other outcomes. DESIGN Prospective matched comparison study. SETTING 54 youth service sites in England. PARTICIPANTS Young people (n=2724) aged 13-15 years at baseline deemed by professionals as at risk of teenage pregnancy, substance misuse,(More)
In recent years numerous new vaccines have been developed, offering potential reductions in the morbidity and mortality caused by a range of diseases. This has led to increased interest in decision-making about the adoption of new vaccines into national immunization programmes. This paper aims to systematically review the literature on national(More)
BACKGROUND In research, diagrams are most commonly used in the analysis of data and visual presentation of results. However there has been a substantial growth in the use of diagrams in earlier stages of the research process to collect data. Despite this growth, guidance on this technique is often isolated within disciplines. METHODS A multidisciplinary(More)
OBJECTIVE This article reviews the evidence for the effectiveness of non-clinical interventions to reduce maternal mortality in low-income settings and identifies the gaps in the evidence base. METHODS A systematic search was conducted to identify reviews and evaluations of non-clinical interventions to reduce maternal mortality in lower-income countries(More)
OBJECTIVE To review published frameworks that included criteria for the assessment of external validity, applicability and transferability in their assessment of health research. METHODS Five databases were searched for articles relating to the assessment of external validity or applicability and transferability in health research. A coding framework was(More)
As more new and improved vaccines become available, decisions on which to adopt into routine programmes become more frequent and complex. This qualitative study aimed to explore processes of national decision-making around new vaccine adoption and to understand the factors affecting these decisions. Ninety-five key informant interviews were conducted in(More)
BACKGROUND The WHO health systems Building Blocks framework has become ubiquitous in health systems research. However, it was not developed as a research instrument, but rather to facilitate investments of resources in health systems. In this paper, we reflect on the advantages and limitations of using the framework in applied research, as experienced in(More)
Determining whether research findings from one setting are relevant to another is complex and poorly understood. This study aimed to explore the factors affecting whether research from other settings was perceived to be of potential use to those working in or researching maternal health in Ghana. Semi-structured interviews were conducted with 69 purposively(More)
OBJECTIVE We aimed to explore the impacts of new vaccine introductions on immunization programmes and health systems in low- and middle-income countries. METHODS We conducted case studies of seven vaccine introductions in six countries (Cameroon, PCV;Ethiopia, PCV; Guatemala, rotavirus; Kenya, PCV; Mali, Meningitis A; Mali, PCV; Rwanda, HPV). Inter-views(More)
BACKGROUND Little is known about the process of assessing whether research conducted in one setting is applicable (i.e. implementable) and transferable (i.e. as effective) to another, despite its importance for health policy and practice. Applicability/transferability differs from external validity; the former focuses on potential utility in another(More)