Helen-Caroline Räwer

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Atopic dermatitis (AD) is a clinically defined, highly pruritic, chronic inflammatory skin disease. In AD patients, the combination of a genetic predisposition for skin barrier dysfunction and dysfunctional innate and adaptive immune responses leads to a higher frequency of bacterial and viral skin infections. The innate immune system quickly mobilizes an(More)
BACKGROUND Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. OBJECTIVE We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the administration of corticosteroids esterified with succinate. METHODS Skin tests, basophil activation tests(More)
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