Helen A Ingram

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Sensory-motor integration has frequently been studied using a single-step change in a control variable such as prismatic lens angle and has revealed human visuomotor adaptation to often be partial and inefficient. We propose that the changes occurring in everyday life are better represented as the accumulation of many smaller perturbations contaminated by(More)
The role of proprioception in the control and adaptation of visuomotor relationships is still unclear. We have studied a deafferented subject, IW, and control subjects in a task in which they used single joint elbow extension to move to a visual target, with visual feedback of the terminal position provided by a cursor displayed in the plane of their(More)
It is not yet certain which sources of information are most important in judging the weight of a held object. In order to study this question further, a "deafferented" man and five controls flexed their wrist to lift a container weighing 1000 g. Direct vision of the arm and weight was denied; the container's vertical position was displayed to the subjects(More)
Visuomotor control of the arm was assessed in a single case study of a subject with focal lesions in the cerebellum and brainstem. A dissociation between 'on-line' and 'off-line' visuomotor control was revealed: impairments in 'on-line' visuomotor control included inaccuracy of tracking velocity, increase in spatial pointing variability and a delay in(More)
The therapeutic effect of iron (Fe) chelators on the potentially toxic plasma pool of nontransferrin-bound iron (NTBI), often present in Fe overload diseases and in some cancer patients during chemotherapy, is of considerable interest. In the present investigation, several multidentate pyridinones were synthesized and compared with their bidentate analogue,(More)
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