Heleen Beckerman

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Changes in scores on health status questionnaires are difficult to interpret. Several methods to determine minimally important changes (MICs) have been proposed which can broadly be divided in distribution-based and anchor-based methods. Comparisons of these methods have led to insight into essential differences between these approaches. Some authors have(More)
The object of this article was to systematically review available methods to measure comorbidity and to assess their validity and reliability. A search was made in Medline and Embase, with the keywords comorbidity and multi-morbidity, to identify articles in which a method to measure comorbidity was described. The references of these articles were also(More)
The aim of this study is to show the relationship between test-retest reproducibility and responsiveness and to introduce the smallest real difference (SRD) approach, using the sickness impact profile (SIP) in chronic stroke patients as an example. Forty chronic stroke patients were interviewed twice by the same examiner, with a 1-week interval. All(More)
OBJECTIVES To determine the intra- and interrater reliability of the Action Research Arm (ARA) test, to assess its ability to detect a minimal clinically important difference (MCID) of 5.7 points, and to identify less reliable test items. DESIGN Intrarater reliability of the sum scores and of individual items was assessed by comparing (1) the ratings of(More)
BACKGROUND AND PURPOSE The Motor Activity Log (MAL) is a semistructured interview for hemiparetic stroke patients to assess the use of their paretic arm and hand (amount of use [AOU]) and quality of movement [QOM]) during activities of daily living. Scores range from 0 to 5. The following clinimetric properties of the MAL were quantified: internal(More)
Minimally important changes (MIC) in scores help interpret results from health status instruments. Various distribution-based and anchor-based approaches have been proposed to assess MIC. To describe and apply a visual method, called the anchor-based MIC distribution method, which integrates both approaches. Using an anchor, patients are categorized as(More)
Kunkel and colleagues 1 recently published an article on constraint-induced (CI) movement therapy for motor recovery in chronic stroke patients. They presented the results of an uncontrolled series of 5 stroke patients undergoing CI therapy. The authors also presented a review of five studies, including their own, concerning the effectiveness of CI therapy(More)
OBJECTIVE To determine the quality of randomised controlled trials of exercise therapy for back pain. DESIGN Computer aided search of published papers and blinded assessment of the methods of studies. SUBJECTS 23 randomised controlled trials, of which 16 studied exercise therapy given by physiotherapists to individual patients with back pain. Other(More)
OBJECTIVE Assessment of the available evidence for the effectiveness of exercise therapy to improve arm function in patients who have suffered from a stroke. METHODS A systematic search of bibliographical databases and reference checking were performed to identify publications on randomized controlled trials (RCTs) which evaluated the effect of exercise(More)
Objective To test the efficacy of 4-aminopyridine (4-AP) on functional status, walking speed and vibration perception in patients with chronic, incomplete spinal cord injury. Methods Twenty SCI patients were randomized in a trial with a double-blind, crossover design to receive four weeks of orally administered 4-AP, followed by a two-week wash-out period(More)