Heinz C. Schröder

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Expression of silicatein and collagen genes in the marine sponge Suberites domuncula is controlled by silicate and myotrophin.

Anatoli Krasko, Bettina Lorenz, Renato Batel, Heinz C. Schröder, Isabel M. Müller, Werner E. G. Müller
European journal of biochemistry
2000

The major skeletal elements in the (Porifera) sponges, are spicules formed from inorganic material. The spicules in the Demospongiae class are composed of hydrated, amorphous silica. Recently an… (More)

Formation of siliceous spicules in the marine demosponge Suberites domuncula

Werner E G Müller, Matthias Rothenberger, Alexandra Boreiko, Wolfgang Tremel, Andreas Reiber, Heinz C. Schröder
Cell and Tissue Research
2005

The siliceous skeleton of demosponges is constructed of spicules. We have studied the formation of spicules in primmorphs from Suberites domuncula. Scanning electron microscopy and transmission… (More)

Co-expression and functional interaction of silicatein with galectin: matrix-guided formation of siliceous spicules in the marine demosponge Suberites domuncula.

Heinz C. Schröder, Alexandra Boreiko, +6 authors Werner E G Müller
The Journal of biological chemistry
2006

Sponges (phylum Porifera) of the class of Demospongiae are stabilized by a siliceous skeleton. It is composed of silica needles (spicules), which provide the morphogenetic scaffold of these… (More)

Iron induces proliferation and morphogenesis in primmorphs from the marine sponge Suberites domuncula.

Anatoli Krasko, Heinz C. Schröder, +4 authors Werner E G Müller
DNA and cell biology
2002

Dissociated cells from marine demosponges retain their proliferation capacity if they are allowed to form special aggregates, the primmorphs. On the basis of incorporation studies and septin gene… (More)

Siliceous spicules in marine demosponges (example Suberites domuncula).

Werner E G Müller, Sergey I. Belikov, +4 authors Heinz C. Schröder
Micron
2006

All metazoan animals comprise a body plan of different complexity. Since--especially based on molecular and cell biological data--it is well established that all metazoan phyla, including the… (More)

Bioorganic/inorganic hybrid composition of sponge spicules: matrix of the giant spicules and of the comitalia of the deep sea hexactinellid Monorhaphis.

Werner E G Müller, Xiaohong Wang, +9 authors Heinz C. Schröder
Journal of structural biology
2008

The giant basal spicules of the siliceous sponges Monorhaphis chuni and Monorhaphis intermedia (Hexactinellida) represent the largest biosilica structures on earth (up to 3m long). Here we describe… (More)

Upregulation of the 2-5A synthetase/RNase L antiviral pathway associated with chronic fatigue syndrome.

Robert J. Suhadolnik, Nancy L. Reichenbach, +7 authors W. A. Carter
Clinical infectious diseases : an official…
1994

Levels of 2',5'-oligoadenylate (2-5A) synthetase, bioactive 2-5A, and RNase L were measured in extracts of peripheral blood mononuclear cells (PBMCs) from 15 individuals with chronic fatigue syndrome… (More)

Bauplan of urmetazoa: basis for genetic complexity of metazoa.

Werner E G Müller, Matthias Wiens, Teresa Adell, V. Gamulin, Heinz C. Schröder, Isabel M. Müller
International review of cytology
2004

Sponges were first grouped to the animal-plants or plant-animals then to the Zoophyta or Mesozoa and finally to the Parazoa. Only after the application of molecular biological techniques was it… (More)

Osteogenic Potential of Biosilica on Human Osteoblast-Like (SaOS-2) Cells

Matthias Wiens, Xiaohong Wang, +5 authors Werner E G Müller
Calcified Tissue International
2010

Biosilica is a natural polymer, synthesized by the poriferan enzyme silicatein from monomeric silicate substrates. Biosilica stimulates mineralizing activity and gene expression of SaOS-2 cells. To… (More)

Inorganic polymeric phosphate/polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca2+ level in osteoblasts (SaOS-2 cells) in vitro.

Werner E G Müller, Xiaohong Wang, +6 authors Heinz C. Schröder
Acta biomaterialia
2011

Inorganic polymeric phosphate is a physiological polymer that accumulates in bone cells. In the present study osteoblast-like SaOS-2 cells were exposed to this polymer, complexed in a 2:1… (More)

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