Heike Cappel-Porter

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BACKGROUND Patients with neovascular age-related macular degeneration (nAMD) usually attend regular reviews, even when the disease is quiescent. Reviews are burdensome to health services, patients and carers. OBJECTIVES To compare the proportion of correct lesion classifications made by community-based optometrists and ophthalmologists from vignettes of(More)
Objectives IVAN and TANDEM are factorial randomised controlled trials (RCTs) of different treatment regimens for wet AMD, involving off-label use of bevacizumab. Safety data are being collected but, given follow-up visits every 4-8 weeks for up to 3 years and verbatim reporting, are difficult to collate. We have developed a database solution for the TANDEM(More)
OBJECTIVES To assess the cost-effectiveness of optometrist-led follow-up monitoring reviews for patients with quiescent neovascular age-related macular degeneration (nAMD) in community settings (including high street opticians) compared with ophthalmologist-led reviews in hospitals. DESIGN A model-based cost-effectiveness analysis with a 4-week time(More)
Background Data from the recent UK-wide registration process for clinical trials units (CTU) revealed that a significant proportion of units use in-house developed solutions despite the availability of numerous commercial and open source solutions, suggesting these solutions may not meet individual trial requirements. Recognising the need to develop(More)
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