Heidrun Losert

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BACKGROUND Platelet activation is a hallmark of acute coronary syndromes. Numerous lines of evidence suggest a mechanistic link between von Willebrand factor or platelet hyperfunction and myocardial damage in patients with acute coronary syndromes. Thus, we assessed whether platelet function under high shear rates (collagen adenosine diphosphate closure(More)
BACKGROUND AND PURPOSE Recently 2 randomized trials in comatose survivors of cardiac arrest documented that therapeutic hypothermia improved neurological recovery. The narrow inclusion criteria resulted in an international recommendation to cool only a restricted group of primary cardiac arrest survivors. In this retrospective cohort study we investigated(More)
Several studies have shown that the carotid pulse check is time-consuming and inaccurate. The sensitivity and specificity of manual pulse check has been reported to be 90% and 55% respectively. It has been suggested that circulatory information can be acquired by measuring the thoracic impedance via the defibrillator pads. We established a dataset of(More)
It has been suggested to acquire circulatory information from patients undergoing resuscitation from cardiac arrest by analyzing their thoracic electrical impedance using modified automated external defibrillators (AEDs). To investigate the potential of this idea, we studied the correlation between two impedance-derived parameters related to circulation,(More)
INTRODUCTION Targeted temperature management improves outcome after cardiopulmonary resuscitation. Reduction of resting energy expenditure might be one mode of action. The aim of this study was to correlate resting energy expenditure and substrate oxidation rates with targeted temperature management at 33°C and outcome in patients after cardiac arrest. (More)
BACKGROUND Despite it being generally regarded as futile, patients are regularly brought to the emergency department with ongoing cardiopulmonary resuscitation (CPR). METHODS Long-term outcome and its predictors in patients who were transported during ongoing CPR were evaluated in an observational study. Adult patients with non-traumatic cardiac arrest(More)
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