Heidi A. Hanson

Learn More
BACKGROUND Triple-negative (TN) tumours are the predominant breast cancer subtype in BRCA1 mutation carriers. Recently, it was proposed that all individuals below 50 years of age with TN breast cancer should be offered BRCA testing. We have evaluated the BRCA1 mutation frequency and the implications for clinical practice of undertaking genetic testing in(More)
Women with BRCA1/2 mutations have a significantly higher lifetime risk of developing breast or ovarian cancer. We suggest that female mutation carriers may have improved fitness owing to enhanced fertility relative to non-carriers. Here we show that women who are carriers of BRCA1/2 mutations living in natural fertility conditions have excess fertility as(More)
BACKGROUND A burgeoning literature links attributes of neighbourhoods' built environments to residents' physical activity, food and transportation choices, weight, and/or obesity risk. In cross-sectional studies, non-random residential selection impedes researchers' ability to conclude that neighbourhood environments cause these outcomes. METHODS(More)
Prostate cancer incidence is sensitive to screening practices, however the impact of recent screening recommendations from the United States Preventative Services Task Force on prostate cancer incidence by age, stage, race, and Gleason score is unknown. This study described the timing and magnitude of changes in prostate cancer incidence trends in the(More)
OBJECTIVE Several studies have suggested that cancer is associated with a reduced risk of the development of Alzheimer's disease (AD). This study seeks to improve our understanding of the association between cancer and the development of AD by showing how mortality selection alters this relationship. METHOD A retrospective cohort study was carried out(More)
BACKGROUND/OBJECTIVES To examine how a woman's current body mass index (BMI) is associated with nonrandom residential migration that is based on the average BMI of her origin and destination neighborhoods. SUBJECTS/METHODS Among women having at least two children, all birth certificates from Salt Lake county from 1989 to 2010 (n=34 010) were used to(More)
OBJECTIVES Empirical studies of the association between neighbourhood food environments and individual obesity risk have found mixed results. One possible cause of these mixed findings is the variation in neighbourhood geographic scale used. The purpose of this paper was to examine how various neighbourhood geographic scales affected the estimated(More)
  • Ir K C A M Luyben, M J F Stive, Rector Magnificus, R Ranasinghe, Universiteit P Hoekstra, J A Utrecht +5 others
  • 2013
The Title of this thesis relates to the pioneering and inspiring work of R.A. Bagnold; " The Physics of Blown Sand and Desert Dunes ". It is not the intention to compare this thesis that took 4 years to complete to the fantastic lifetime legacy of R.A. Bagnold. The work of R.A. Bagnold continues to inspire and with using this title it is intended to make a(More)