Heejeong Kim

Hyunwon Yang3
Soyong Jang2
3Hyunwon Yang
2Soyong Jang
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Previously, a missense polymorphism was identified in the mouse nicotinic receptor alpha4 subunit gene, Chrna4. This polymorphism leads to an Ala/Thr variation at amino acid position 529 of the alpha4 subunit. Chrna4 A529T is associated with several measures of acute sensitivity to nicotine as well as with mouse strain differences in nicotine-stimulated(More)
In this study, we investigated the neuroprotective effect of a benzylideneacetophenone derivative, JC3, in a mouse model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease (PD). C57BL/6 mice were treated with MPTP (30 mg/kg, i.p.) for 5 consecutive days. JC3 (10 mg/kg, i.p.) treatment was initiated 2 h after the first(More)
Morphine has been used widely on the treatment of many types of chronic pain. However the development of tolerance to and dependence on morphine by repeat application is a major problem in pain therapy. The purpose of the present study was to investigate whether combined administration of nalbuphine with morphine affects the development of tolerance to and(More)
The pregnancy and abortion process involves a complex mechanism with various immune cells present in the implantation sites and several hormones associated with pregnancy, such as leptin, ghrelin and nesfatin-1. However, the mechanism underlying spontaneous abortion by maternal T helper 17 (Th17) present in the implantation sites and nesfatin-1, which is of(More)
We studied the mechanism by which tributylin acetate (TBT) inhibits the development of T cells in the mouse thymus. After 7 days of oral TBT administration in mice, thymic weights were significantly decreased, and the expression of Troma-1, a thymic cortical epithelial cell marker, was also decreased in TBT-treated mice. The expression of cytokines produced(More)
Nesfatin-1, an anorexic nucleobindin-2 (NUCB2)-derived hypothalamic peptide, controls appetite and energy metabolism. Recent studies show that nesfatin-1/NUCB2 is expressed not only in the brain but also in gastric and adipose tissues. Thus, we investigated the distributions of nesfatin-1/NUCB2 in various tissues of male and female mice by real-time PCR,(More)
Recently, mobile TV is becoming a mainstream service in mobile broadcasting scenario, where requires lots of mobile factors such as robust transmission, high performance and easy interface and so on. As mobile broadcasting services are being highlighted, the easy interface and appropriate application are increasingly in demand. In most mobile scenarios,(More)
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