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Pharmacokinetics, Pharmacodynamics, and Tolerability of Single-Dose Oral LCB01-0371, a Novel Oxazolidinone with Broad-Spectrum Activity, in Healthy Volunteers
- Yong-Soon Cho, Hyeong-Seok Lim, Shi-Hyang Lee, Y. L. Cho, Hee-sook Nam, K. Bae
- Antimicrobial Agents and Chemotherapy
- 30 April 2018
ABSTRACT LCB01-0371 is a novel oxazolidinone with broad-spectrum activity against Gram-positive pathogens in both in vitro studies and animal infection models. The objectives of this study were to… Expand
Single-dose Intravenous Safety, Tolerability, and Pharmacokinetics and Absolute Bioavailability of LCB01-0371.
PURPOSE LCB01-0371 is a novel broad-spectrum oxazolidinone antibacterial agent under investigation for the treatment of infection by gram-positive pathogens, including methicillin-resistant… Expand
Multiple-dose Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral LCB01-0371 in Healthy Male Volunteers.
- Yong-Soon Cho, Hyeong-Seok Lim, Y. L. Cho, Hee-sook Nam, K. Bae
- Clinical therapeutics
- 1 December 2018
PURPOSE LCB01-0371 is a novel oxazolidinone broad-spectrum antibacterial that is more potent than linezolid against systemic infections in animals. The goal of this investigation was to evaluate the… Expand
Publication of Buddhist Literary Texts: The Publication and Popularization of Mantra Collections and Buddhist Ritual Texts in the Late Chosŏn Dynasty
It is commonly maintained by scholars of Chosŏn era Buddhism that the Chosŏn Dynasty’s enforcement of the sungyu ŏkpul 崇儒抑佛 (“promote Confucianism, reject Buddhism”) policy resulted in a Buddhism… Expand