Hee Young Kim

Chae Ha Yang15
Bong Hyo Lee13
Dong Seop Choi12
Sin Gon Kim12
Kyungsoon Chung10
15Chae Ha Yang
13Bong Hyo Lee
12Dong Seop Choi
12Sin Gon Kim
10Kyungsoon Chung
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Reactive oxygen species (ROS) scavengers have been shown to relieve persistent pain; however, the mechanism is not clearly understood. Superoxide produced from mitochondrial oxidative phosphorylation is considered the major source of ROS in neurons during excitation where mitochondrial superoxide levels are normally controlled by superoxide dismutase(More)
  • June Yowtak, Kwan Yeop Lee, Hee Young Kim, Jigong Wang, Hee Kee Kim, Kyungsoon Chung +1 other
  • 2011
Although both a loss of spinal inhibitory neurotransmission and the involvement of oxidative stress have been regarded as important mechanisms in the pathogenesis of pain, the relationship between these 2 mechanisms has not been studied. To determine whether reactive oxygen species (ROS) involvement in pain mechanisms is related to the diminished inhibitory(More)
BACKGROUND Understanding the health status of North Korean refugees (NKRs), and changes in health during the resettlement process, is important from both the humanitarian standpoint and the scientific perspective. The NOrth Korean Refugee health iN South Korea (NORNS) study aims to document the health status and health determinants of North Korean refugees,(More)
The increase of cytosolic free Ca(2+) ([Ca(2+)](c)) due to NMDA receptor activation is a key step for spinal cord synaptic plasticity by altering cellular signal transduction pathways. We focus on this plasticity as a cause of persistent pain. To provide a mechanism for these classic findings, we report that [Ca(2+)](c) does not trigger synaptic plasticity(More)
  • Hee Young Kim, Jigong Wang, Inhyung Lee, Hee Kee Kim, Kyungsoon Chung, Jin Mo Chung
  • 2009
Central sensitization, caused either by tissue inflammation or peripheral nerve injury, plays an important role in persistent pain. An animal model of capsaicin-induced pain has well-defined peripheral and central sensitization components, thus is useful for studying the analgesic effect on two separate components. The focus of this study is to examine the(More)
The primo vascular structures comprising primo nodes and vessels (originally called Bonghan corpuscles and ducts, resp.) have recently been suggested to be the anatomical correlate of acupuncture, a therapeutic technique used in oriental medicine. Although the primo vascular structures have been observed in many parts of animals, including the nervous(More)
OBJECTIVES Acupuncture, an alternative medical therapy with a long history, is appealing because it can activate endogenous analgesic mechanisms by minimally invasive means. The mechanisms of acupuncture, however, are not well understood yet. The following sentence was removed from our original manuscript. One of the major problems impeding understanding of(More)
BACKGROUND This study was designed to evaluate the clinical, endocrinological and histological characteristics of adrenal incidentalomas. METHODS Eighty patients (41, males; 38, females; age range 17-80 years) who were diagnosed with adrenal incidentaloma at Korea University Hospital from 1992 to 2003 were studied retrospectively. RESULTS(More)
  • June Yowtak, Jigong Wang, Hee Young Kim, Ying Lu, Kyungsoon Chung, Jin Mo Chung
  • 2013
One feature of neuropathic pain is a reduced spinal gamma-aminobutyric acid (GABA)-ergic inhibitory function. However, the mechanisms behind this attenuation remain to be elucidated. This study investigated the involvement of reactive oxygen species in the spinal GABA neuron loss and reduced GABA neuron excitability in spinal nerve ligation (SNL) model of(More)
Dengue virus is a mosquito-borne flavivirus that has a large impact in global health. It is considered as one of the medically important arboviruses, and developing a preventive or therapeutic solution remains a top priority in the medical and scientific community. Drug discovery programs for potential dengue antivirals have increased dramatically over the(More)