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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease, characterized by the predominant loss of motor neurons (MNs) in primary motor cortex, the brainstem, and the spinal cord, causing premature death in most cases. Minimal delay of pathological development by available medicine has prompted the search for novel therapeutic treatments to cure(More)
This paper presents a novel CMOS charge transfer readout circuit for X-ray time delay and integration (TDI) arrays with a depth of 64. The proposed circuit uses a charge transfer readout similar to CCD; thus, the summing of the signal charges can be implemented easily compared with other typical CMOS readout circuits for TDI arrays. The weakness of TDI(More)
Granule exocytosis-mediated cytotoxicity by CD8(+) CTL plays a crucial role in adaptive immunity to tumors and to intracellular pathogens. This T cell effector function has been shown to be defective in various murine tumor models and in human cancer. However, factors and their mechanisms that cause inhibition of CD8(+) T cell lytic function in(More)
PURPOSE Active reduced dose tetanus-diphtheria-acellular pertussis (Tdap) vaccination for adolescents and adults is necessary because waning immunity after primary diphtheria-tetanus-pertussis vaccination is related to the recent emergence of pertussis. This study was conducted to compare the immunogenicity and protection efficacy against Bordetella(More)
—A new readout circuit involving two-step current mode background suppression is studied for two-dimensional long-wavelength infrared focal plane arrays (2-D LWIR FPAs). Buffered direct injection (BDI) and a feedback amplifier are used for the input circuit and background suppression circuit, respectively. The readout circuit has been fabricated using a(More)
This study investigated the morphological and electromechanical characteristics of 0.2PZN-0.8PZT films fabricated using a PbTiO3 layer. Crack-free 1-microm-thick films with a pure perovskite phase were obtained on Pt/Ti/SiO2/Si substrates using a modified sol-gel deposition method. A highly dense and smooth morphology and a high piezoelectric coefficient(More)
Pure SnO2 nanoparticles with a single tetragonal phase were fabricated and characterized for use as ink solution. It was possible to obtain the SnO2 nanoparticles through the calcination process of SnC204 powders prepared by a hydrothermal reaction of an aqueous solution containing SnCl2 x 2H2O and H2C2O4. The SnO2 powder, synthesized at 600 degrees C,(More)