Hedia Fgaier

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In a standard procedure of food safety testing, the presence of the pathogenic bacterium Listeria monocytogenes can be masked by non-pathogenic Listeria. This phenomenon of Listeria overgrowth is not well understood. We present a mathematical model for the growth of a mixed population of L. innocua and L. monocytogenes that includes competition for a common(More)
Iron is required by many microorganisms for growth. Although it is the most abundant transition metal on earth, its solubility is very low and therefore its bioavailability is poor. To overcome this limitation, many microorganisms have developed iron chelating mechanisms that enable them to bind the metal to organic molecules from which they are later(More)
Certain bacteria develop iron chelation mechanisms that allow them to scavenge dissolved iron from the environment and to make it unavailable to competitors. This is achieved by producing siderophores that bind the iron which is later liberated internally in the cell. Under conditions of iron limitation, siderophore producing bacteria have therefore an(More)
In this study we present a competition model between a non-chelator (e.g. pathogen) microorganism and an iron chelator microorganism (e.g. Pseudomonas fluorescens). This latter is a beneficial bacteria that can inhibit the growth of the non-chelator through its iron chelating capability. This phenomena of iron chelation is shown to prevent the pathogen from(More)
The effect of β-amyloid aggregates on activity of choline acetyltransferase (ChAT) which is responsible for synthesizing acetylcholine (ACh) in human brain is investigated through the two-enzyme/two-compartment (2E2C) model where the presynaptic neuron is considered as compartment 1 while both the synaptic cleft and the postsynaptic neuron are considered as(More)
The a priori knowledge about biodegradability is adopted to save time and money for research and design of new products. Quantitative structure activity relationship (QSAR) models as a tool for biodegradability prediction of chemicals have been encouraged by environmental organizations. In the current work, a new algorithm has been proposed to investigate(More)
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