Hedi L. Claahsen-van der Grinten

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Objective: Testicular adrenal rest tumours (TART) are a well-known complication in adult male patients with congenital adrenal hyperplasia (CAH), with a reported prevalence of up to 94%. In adulthood, the tumours are associated with gonadal dysfunction most probably due to longstanding obstruction of the seminiferous tubules. The aim of our study was to(More)
The aim of the present study was to investigate the pharmacokinetic profile of tramadol hydrochloride in neonates, born from mothers who underwent analgesia with tramadol for the relief of labour pain. Intramuscular tramadol (100–250 mg) was administered to 22 mothers giving birth who requested pain relief. At the time of birth (1.5–6.0 h after last(More)
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