Hebbur Shivamurthy Bharath

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In the title compound, C7H4F2O3, an intra-molecular O-H⋯O hydrogen bond is observed. In the crystal, inversion dimers linked by pairs of O-H⋯O hydrogen bonds generate R 2 (2)(8) ring motifs. These dimers are linked by C-H⋯O and C-H⋯F hydrogen bonds, forming sheets lying parallel to (30-1). The sheets are linked by aromatic π-π stacking inter-actions(More)
Herein method for the synthesis of substituted 1,2benzoxazolone (8a-f) and 3-chloro-1,2-benzoxazole (9a-f) derivatives has been described. A new scheme has been adapted for the construction of 1,2benzoxazole ring from salicylic acid and its derivatives which leads to the formation of series of 5,6 and 7 substituted title compounds. Synthesized compounds(More)
Gingival overgrowth is a common side-effect of the administration of cyclosporin A (CSA), phenytoin, and calcium blockers. To identify the signaling mechanisms possibly involved in the overgrowth, we examined how CSA affects the activities of MAP kinases and transcription factors in human gingival fibroblasts (HGF). The HGF were treated with CSA and(More)
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