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- Stuart J Macdonald, Heba H. Mostafa, Lynda A Morrison, David J. Davido
- Journal of virology
- 2012
Herpes simplex virus type 1 (HSV-1) strain KOS has been extensively used in many studies to examine HSV-1 replication, gene expression, and pathogenesis. Notably, strain KOS is known to be less… (More)
- Heba H. Mostafa, Peter Vogel, A. V. Srinivasan, Charles J Russell
- PLoS pathogens
- 2016
In immunocompromised patients, parainfluenza virus (PIV) infections have an increased potential to spread to the lower respiratory tract (LRT), resulting in increased morbidity and mortality.… (More)
- Stuart J Macdonald, Heba H. Mostafa, Lynda A Morrison, David J. Davido
- Journal of virology
- 2012
The herpes simplex virus 1 (HSV-1) strain McKrae is highly virulent compared to other wild-type strains of HSV-1. To help us better understand the genetic determinants that lead to differences in the… (More)
The herpes simplex virus type 1 (HSV-1) encoded E3 ubiquitin ligase, infected cell protein 0 (ICP0), is required for efficient lytic viral replication and regulates the switch between the lytic and… (More)
- Marion Russier, Guohua Yang, +8 authors Charles J Russell
- Proceedings of the National Academy of Sciences…
- 2016
Influenza pandemics require that a virus containing a hemagglutinin (HA) surface antigen previously unseen by a majority of the population becomes airborne-transmissible between humans. Although the… (More)
- Heba H. Mostafa, Thornton W Thompson, David J. Davido
- Journal of virology
- 2013
The herpes simplex virus 1 (HSV-1) infected cell protein 0 (ICP0) is an immediate-early phosphoprotein that transactivates viral gene expression. Evidence suggests that phosphorylation regulates the… (More)
- Mirna Perusina Lanfranca, Heba H. Mostafa, David J. Davido
- Journal of virology
- 2013
Herpes simplex virus 1 (HSV-1) establishes a lifelong latent infection in sensory neurons and can reactivate from latency under stress conditions. To promote lytic infection, the virus must interact… (More)
- Heba H. Mostafa, Thornton W Thompson, +8 authors David J. Davido
- Journal of virology
- 2011
In cell culture experiments, phosphorylation appears to be a critical regulator of the herpes simplex virus 1 (HSV-1) immediate-early (IE) protein, ICP0, which is an E3 ubiquitin ligase that… (More)
- Heba H. Mostafa, David J. Davido
- Journal of virology
- 2013
The herpes simplex virus 1 (HSV-1) immediate-early protein, infected cell protein 22 (ICP22), is required for efficient replication in restrictive cells, for virus-induced chaperone-enriched (VICE)… (More)
- Philippe Noriel Q Pascua, Heba H. Mostafa, +4 authors Elena A Govorkova
- Scientific Reports
- 2017
Influenza B viruses are important human pathogens that remain inadequately studied, largely because available animal models are poorly defined. Here, we developed an immunocompromised murine models… (More)