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Recently genetics and epigenetics alterations have been found to be characteristic of malignancy and hence can be used as targets for detection of neoplasia. RAS association domain family protein 1A (RASSF1A) gene hypermethylation has been a subject of interest in recent researches on cancer breast patients. The aim of the present study was to evaluate(More)
BACKGROUND The potential use of microRNAs (miRNAs) as ideal tumor markers has been the focus of recent research. OBJECTIVE Our hypothesis was that circulating miRNAs are differentially expressed in pretherapeutic sera of breast cancer patients compared to controls. MATERIALS AND METHODS Using real-time quantitative polymerase chain reaction (qPCR)(More)
Currently, azoospermia is one of the most common diseases of male infertility. Stem cell research is the new hope for novel therapy with a higher degree of safety and lower cost. This study aimed to investigate the effect of umbilical cord blood-derived stem cells (” and mesenchymal “UCB-MSCs”) and mono-cell layer implanted into the induced azoospermic mice(More)
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