Heather Withers

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OBJECTIVES To determine whether vitamin D supplementation reduces the risk of fracture or falls in elderly people in care home accommodation. DESIGN A randomised controlled trial of cluster design. SETTING AND SUBJECTS 223 Residential units (mainly identical 30-bedded units), within 118 homes for elderly people throughout Britain, with 3,717(More)
Bacterial cell-to-cell communication (quorum sensing) relies upon the interaction of a small diffusible signal molecule with a sensor or transcriptional activator to couple gene expression with cell population density. In Gram-negative bacteria, it is now clear that N-acylhomoserine lactones bind directly to LuxR homologues and can be synthesized via one of(More)
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