Heather M. Bowen

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Mice fed a high-fat diet are reported to be resistant to peripheral injections of leptin. We previously failed to induce leptin resistance in female mice fed a high-fat diet for 15 weeks. Therefore, we measured the responsiveness to peripheral infusions (10 microg/day) of leptin, and the responsiveness to third ventricle injections of leptin (1 microg) in(More)
High-fat diets are reported to induce resistance to peripherally administered leptin. In an attempt to develop a model of juvenile diet-induced obesity, mice were weaned onto high-fat diet. Male and female, 35-day-old, C57BL/6J high-fat (45% kcal fat) diet-fed mice housed individually on grid floors did not decrease food intake or body weight in response to(More)
OBJECTIVE To describe the development, reliability, and validity of the Environmental Assessment Tool (EAT) for assessing worksite physical and social environmental support for obesity prevention. METHODS The EAT was developed using a multistep process. Inter-rater reliability was estimated via Kappa and other measures. Concurrent and predictive validity(More)
OBJECTIVE To assess the ability of the Environmental Assessment Tool (EAT) to detect changes over time in workplace physical and social environmental supports for physical activity and nutrition; and predict employee engagement, behavior changes, and biometrics. METHODS Analyses utilized site-level (n = 12) EAT scores. Differences-in-difference(More)