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OVERVIEW The United States continues to have one of the highest teen birth rates in the developed world, 1 and adolescent rates of sexually transmitted infections (STIs) are also high. 2 These factors highlight the need to identify effective evidence-based programs to improve adolescent reproductive health. This brief synthesizes findings from 118(More)
BACKGROUND US adolescents have high rates of teen pregnancy, childbearing, and sexually transmitted infections (STIs), highlighting the need to identify and implement effective programs that will help improve teen sexual and reproductive health. MATERIALS AND METHODS This review identified 103 random-assignment evaluations of 85 programs that incorporated(More)
A calibrated competitive NMR method has been developed that is appropriate for the rapid screening of binding constants. This method involves the initial characterisation of a receptor-substrate binding event for which the (1)H NMR spectrum of a given receptor (calibrant) is modified by the substrate of interest at a range of concentrations. For all(More)
Cushing's syndrome associated with macronodular adrenal hyperplasia (MAH) may present with high-dose dexamethasone (dex) nonsuppressible hypercortisolemia. This has been interpreted as suggesting a primary adrenal disorder, leading to recommendations for curative adrenalectomy in these cases. The present case of MAH demonstrates high urinary and serum(More)
Overwhelming postsplenectomy infection (OPSI) due to group B streptococcus developed in an insulin-dependent diabetic patient. The illness began with nonspecific symptoms, followed rapidly by hypotension and disseminated intravascular coagulation. The early institution of appropriate antibiotics, fluid replacement and pressor agents resulted in a favorable(More)
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