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BACKGROUND Birth weight is inversely associated with cardiovascular disease risk factors, but few studies have examined the association with disease end points, in particular with stroke risk. Furthermore, previous studies demonstrating an inverse association between birth weight and coronary heart disease (CHD) risk have been conducted on populations born(More)
OBJECTIVES We assessed the associations of childhood socioeconomic position with cardiovascular disease risk factors (smoking, binge alcohol drinking, and being overweight) and examined the roles of educational attainment and cognitive functioning in these associations. METHODS Data were derived from a cohort study involving 7184 individuals who were born(More)
BACKGROUND Although adult reported childhood socioeconomic position has been related to health outcomes in many studies, little is known about the validity of such distantly recalled information. This study evaluated the validity of adults' reports of childhood paternal social class. METHODS Data are drawn from the Aberdeen children of the 1950s study, a(More)
OBJECTIVE To estimate the rate of spontaneous preterm delivery and preterm premature rupture of membranes (PROM) in women with cervical intraepithelial neoplasia (CIN) 3. METHODS This retrospective cohort analysis was performed on routinely collected Scottish national data. The exposed cohort comprised all women with CIN3; the unexposed cohort were women(More)
BACKGROUND Little is known about the relationship between early life factors and survey response in epidemiological studies of adults. METHODS The Children of the 1950s cohort is composed of 12,150 children (boys 51.7%) born in Aberdeen 1950-56 and in primary schools in the city in 1962. Information on birth weight, gestational age, growth, behaviour and(More)
Objectives Associations of cognitive function assessed in adulthood with coronary heart disease (CHD) and stroke might reflect a causal effect or could be explained by residual confounding or a common underlying pathology (atherosclerosis) that links both declines in cognitive function and increased risk of cardiovascular disease (i.e. reverse causality).(More)
OBJECTIVES We assessed the association of father's social class, recorded at the time of birth, with coronary heart disease and stroke in a British cohort of 11106 individuals born in the 1950s. METHODS Survival analysis was used to relate social class at birth to the occurrence of either fatal or nonfatal coronary heart disease or stroke. RESULTS Rates(More)