Hean-chooi Ong

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In this paper, we investigated the antibacterial mechanism and potential therapeutic targets of three antibacterial medicinal plants. Upon treatment with the plant extracts, bacterial proteins were extracted and resolved using denaturing gel electrophoresis. Differentially-expressed bacterial proteins were excised from the gels and subjected to sequence(More)
Ferns contain natural products with potential therapeutic applications. Current knowledge of the pharmacological properties of ferns, specifically those growing at high altitudes, is limited. This study aimed to evaluate the phytochemical contents as well as antibacterial, anti-glucosidase, and antioxidant activities of four highland ferns in Malaysia.(More)
Stenochlaena palustris is an edible fern that is used as vegetable and in traditional medicine. This study assessed the total polyphenol, flavonoid, hydroxycinnamic acid and anthocyanin contents, as well as radical scavenging, ferric reducing and metal chelating activities of the extracts of S. palustris. The four extracts analysed were prepared from the(More)
Purpose: To evaluate the phytochemical profile as well as in vitro antioxidant, iron-chelating, and antiglucosidase activities of Typha domingensis Pers. (Typhaceae) Methods: Total polyphenols, flavonoids, hydroxycinnamic acids, and pro-anthocyanidins in the respective aqueous extracts of male and female flowers, and fruit of T. domingensis were determined(More)
The purpose of this investigation was to determine the antioxidant potentials and anti-glucosidase activities of six tropical medicinal plants. The levels of phenolic constituents in these medicinal plants were also quantified and compared. Antioxidation potentials were determined colorimetrically for scavenging activities against DPPH and NO radicals.(More)
BACKGROUND The phytochemistry and bioactivity of wetland macrophytes are underexplored. Plants are known as the natural sources of phytochemical beneficial to health. OBJECTIVE The objective of this study is to analyze the phytochemical profiles and bioactivities of 10 extracts prepared from different plant parts of wetland macrophytes Hanguana malayana,(More)
Purpose: To evaluate the glucosidase inhibitory and cytotoxic activities of five selected edible and medicinal ferns, namely, Blechnum orientale, Davallia denticulata, Diplazium esculentum, Nephrolepis biserrata, and Pteris vittata. Methods: The aqueous extracts of the five ferns were prepared by water extraction at 90 oC for 1 h. Antiglucosidase assay was(More)
Globally, bioactive phytochemicals are gaining popularity among consumers, as evidenced by the steady rise in the demand for botanical dietary supplements. One driving force behind this is the perception of herbal medicine being a safe and relatively inexpensive alternative in the management of human diseases (1, 2). There is currently intensive effort(More)
Purpose: To determine the phenolic constituents as well as anti-proliferative, antioxidant and ironchelating activities of the leaf and rhizome extracts of Phymatopteris triloba. Methods: Concentrations of selected hydroxybenzoic acids, hydroxycinnamic acids and flavonoids in aqueous extracts were quantified using high performance liquid chromatography(More)
This study aimed to isolate a potent antiglucosidase and antioxidant fraction from Stenochlaena palustris. Extraction was performed with hexane, chloroform, ethyl acetate, methanol, and water. Antiglucosidase, 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging and ferric reducing antioxidant power (FRAP) assays found methanol extract (ME) to be the most(More)