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Prolonged low-frequency stimulation of excitatory afferents to basolateral amygdala neurons results in enduring enhancement of excitatory synaptic responses. The induction of this form of synaptic plasticity is eliminated by selective antagonists of GluR5 kainate receptors and can be mimicked by the GluR5 agonist ATPA. Kainate receptor-mediated synaptic(More)
Intense or chronic stress can produce pathophysiological alterations in the systems involved in the stress response. The amygdala is a key component of the brain's neuronal network that processes and assigns emotional value to life's experiences, consolidates the memory of emotionally significant events, and organizes the behavioral response to these(More)
Scalable video coding is an ongoing standard, and the current working draft (WD) is an extension of H.264/AVC. In the WD, an exhaustive search technique is employed to select the best coding mode for each macroblock. This technique achieves the highest possible coding efficiency, but it results in extremely large encoding time which obstructs it from(More)
The occurrence of stress and anxiety disorders has been closely associated with alterations of the amygdala GABAergic system. In these disorders, dysregulation of the serotonergic system, a very important modulator of the amygdala GABAergic system, is also well recognized. The present study, utilizing a learned helplessness stress rat model, was designed to(More)
The activation of kainate receptors modulates GABAergic synaptic transmission, but the mechanisms are currently a matter of intense debate. In the basolateral amygdala (BLA), the glutamate receptor 5 (GluR5) subunit of kainate receptors is heavily expressed, and GluR5 antagonists block a novel form of synaptic plasticity; yet little is known about the role(More)
This study examines forms of activity-dependent synaptic plasticity in the basolateral amygdala in vitro and demonstrates that a brief high frequency stimulus (HFS) train can induce a switch in the direction of the enduring change in synaptic strength induced by subsequent low-frequency stimulation (LFS). LFS (1 Hz, 15 min) of the external capsule (EC)(More)
K-means algorithm is one of the most famous unsupervised clustering algorithms. Many theoretical improvements for the performance of original algorithms have been put forward, while almost all of them are based on Single Instruction Single Data(SISD) architecture processors (CPUs), which partly ignored the inherent paralleled characteristic of the(More)
As the popularity of the social media increases, as evidenced in Twitter, Facebook and China’s Renren, spamming activities also picked up in numbers and variety. On social network sites, spammers often disguise themselves by creating fake accounts and hijacking normal users’ accounts for personal gains. Different from the spammers in traditional systems(More)
The expression and characteristics of beta-adrenoceptor subtypes (beta1 and beta2) and their agonist actions on synaptic transmission in the basolateral amygdala (BLA) of the rat were examined using in situ hybridization, quantitative real-time PCR, Western blot analysis and field potential recording. In situ hybridization data revealed an intense(More)
BACKGROUND AND PURPOSE Activation of Notch worsens ischemic brain damage as antisense knockdown or pharmacological inhibition of the Notch pathway reduces the infarct size and improves the functional outcome in a mouse model of stroke. We sought to determine whether Notch activation contributes to postischemic inflammation by directly modulating the(More)