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Knowledge or experience is voluntarily recalled from memory by reactivation of the neural representations in the cerebral association cortex. In inferior temporal cortex, which serves as the storehouse of visual long-term memory, activation of mnemonic engrams through electric stimulation results in imagery recall in humans, and neurons can be dynamically(More)
EEG data were recorded under field conditions from 11 members of the Santo Daime Doctrine, a Brazilian shamanistic religion, before and after ingesting the psychoactive alkaloid preparation, ayahuasca, or daime, as they term it. Post-ingestion, we observed increases in power in the 36-44 Hz frequency band ("40 Hz") from the left occipital-temporal-parietal(More)
Neuropsychological theories proposed a critical role of the interaction between the medial temporal lobe and neocortex in the formation of long-term memory for facts and events, which has often been tested by learning of a series of paired words or figures in humans. We identify neural mechanisms of this long-term memory formation process by single-unit(More)
We report a 5-year-old boy with lysosomal glycogen storage disease and normal acid maltase activity. This patient, the fourth reported in the literature, was referred to our hospital for evaluation of elevated serum GOT, GPT, and CK activities. He had neither muscle weakness nor atrophy. Echocardiography demonstrated marked thickening of the(More)
OBJECTIVE The aim of this study was to investigate physiological changes in cardiac area and diameters between inspiratory and expiratory chest computed tomography (CT), and to assess their correlation with lung size change and influence on cardiothoracic ratio (CTR) measurements. MATERIALS AND METHODS The institutional review board of our institution(More)
Cardiac muscular biopsies were performed on 4 patients with Duchenne muscular dystrophy (DMD). None of the patients had cardiac symptoms and all of them exhibited normal electro- and echocardiographic findings. Electron microscopic examination of cardiac muscles from 4 patients with DMD disclosed proliferation of the mitochondria, changes in the cristae,(More)
The hemodynamic and right ventricular volumetric effects of disopyramide were investigated in patients with tetralogy of Fallot (TF). Intracardiac pressure and oxygen saturation were measured, before and after intravenous administration of disopyramide (2 mg/kg) in 7 patients who had not had previous surgery. Right ventricular volume and the diameter of its(More)
To understand the biological basis of memory is one of the most exciting frontiers of science. Single unit recording is a powerful method to investigate neuronal correlates of various brain functions such as memory in awake animals. Anatomical, neuropsychological, and neurophysiological evidence indicates that the IT has an important role not only for(More)
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