Haruyuki Watanabe

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T cells play central roles in liver diseases, but the regulatory mechanism by cytokine signaling is not well understood. In the present study, we explored the role of SOCS3 in T cells in concanavalin A (ConA)-induced hepatitis. Mice with T-cell-specific overexpression of SOCS3 (SOCS3-cTg) showed reduced hepatic damage and improved mice survival relative to(More)
In this work, the authors present an effective denoising method to attempt reducing the noise in mammographic images. The method is based on using hierarchical correlation of the coefficients of discrete stationary wavelet transforms. The features of the proposed technique include iterative use of undecimated multi-directional wavelet transforms at adjacent(More)
Computer-aided detection and diagnosis (CAD) systems are increasingly being used as an aid by clinicians for detection and interpretation of diseases. In general, a CAD system employs a classifier to detect or distinguish between abnormal and normal tissues on images. In the phase of classification, a set of image features and/or texture features extracted(More)
OBJECTIVE The purpose of this study is to examine how the fractional b value affects the calculation of apparent diffusion coefficient (ADC) using DWI. The fractional b value is the point of intersection between the fast and slow components of biexponential decay in DWI. SUBJECTS AND METHODS Human brains were imaged using multiple b values on echo-planar(More)
Joint photographic experts group(JPEG)and JPEG2000 are widely used as image compression algorithms in medical image database systems. Compressed images have been mainly evaluated by visual assessment on acceptable compression levels in clinical studies. However, to the best of our knowledge, little work has been done to clarify image properties based on(More)
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