Haruo Toda

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Disrupted-in-schizophrenia-1 (DISC1) is one of major susceptibility factors for a wide range of mental illnesses, including schizophrenia, bipolar disorder, major depression and autism spectrum conditions. DISC1 is located in several subcellular domains, such as the centrosome and the nucleus, and interacts with various proteins, including NudE-like(More)
Electrocorticogram (ECoG) is a well-balanced methodology for stably mapping brain surface local field potentials (LFPs) over a wide cortical region with high signal fidelity and minimal invasiveness to the brain tissue. To directly compare surface ECoG signals with intracortical neuronal activity immediately underneath, we fabricated a flexible multichannel(More)
Convergence eye movements were evoked in the lateral suprasylvian cortex (LS cortex) in the cat. Three effective regions were found: the rostral and caudal parts of the postero-medial LS cortex (the PMLS) and the rostral part of the postero-lateral LS cortex (the PLLS). These three areas represent the central and paracentral visual fields in the published(More)
Changes in visual and oculomotor functions were tested in eight young volunteer subjects after performing a 3-D visually-guided task for 25 min. The visual stimuli were given by using a head-mounted display. No significant change was detected in the AC/A ratio and the stereo acuity. Changes were found in refraction and ocular convergence. Slight but(More)
Open-loop and closed loop controls in convergence eye movement have been reported by human psycho-physical studies. To investigate the visual cortical involvement in open-loop convergence eye movement, we trained a cat to elicit anticipatory convergence (convergence eye movement before the onset of target movement) by using an approaching visual target with(More)
BACKGROUND Taking advantage of developed image technology, it is expected that image presentation would be utilized to promote health in the field of medical care and public health. To accumulate knowledge on biomedical effects induced by image presentation, an essential prerequisite for these purposes, studies on autonomic responses in more than one(More)
The effects of watching video movies on autonomic functions were estimated by measuring changes in pupillary and cardiovascular parameters in 10 senior subjects. The subjects looked at a series of video images (with accompanied sounds) taken during the execution of motor vehicles. The images were rear-projected on a large screen for 15 min. Pupil diameter(More)
We evaluated the effects of electrolytic lesions in the extrastriate cortical area on the amplitudes and velocities of vergence eye movements in six alert cats that were trained to track a target moving in depth. Bilateral or unilateral lesions in the lateral suprasylvian (LS) cortex reduced the amplitudes and velocities of vergence eye movements, but the(More)
We evaluated the accommodative and pupillary responses to sinusoidal target depth movement in 10 normal subjects and one patient by analysing frequency responses and associated Bode plots. The phase of the pupillary response significantly lagged behind that of accommodative response, which suggests that they are controlled by separate central nervous(More)