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Single unit activity was recorded percutaneously with microelectrodes from 38 rapidly adapting (RA) mechanoreceptors of the dorsal surface of the hand in 49 awake human subjects. Tuning characteristics were determined for 28 RA-fibers at various frequencies between 5 and 100 cps of sinusoidal mechanical stimulation. In separate experiments human thresholds(More)
In cats afferent impulses from splanchnic and vagus nerve preparations were studied. In each splanchnic nerve serving the stomach or the adjacent part of the duodenum, cold-sensitive afferents could be recorded. There were also numerous mechanosensitive fibers originating from stomach, intestine, mesentery and the region of blood vessels. No thermal(More)
1. To test whether the preoptic area controls only non-shivering and the spinal cord only shivering thermogenesis, ten rats were chronically implanted with a preoptic and a spinal cord thermode each. The following were then studied: (a) the effect of propranolol (8 mg/kg.hr) on the metabolic response to cooling the preoptic area, and the spinal cord, (b)(More)
Electrophysiological recordings were made from 12 specific warm receptors in the sensory nerves of human hairy skin. In all cases examined, single warm fibers were spontaneously active at normal skin temperature from about 32 degrees C upwards, while touch, stretching, vibration or pricking the skin did not elicit any response within the receptive fields of(More)
1. The technique of single fibre dissection has been used to study the warm and cold thermoreceptors in the rat scrotum. 2. The warm receptors showed dynamic activity during increases of scrotal temperature and static activity when temperature was constant. The static activity/temperature curve was bell-shaped, with minima at 31 and 45 degrees C and a peak(More)
The response of slowly conducting myelinated and unmyelinated afferent units to natural types of cutaneous stimuli was recorded extracellularly with tungsten microelectrodes from intact human skin nerves. Seven fibers had characteristics of C-polymodal units (conduction velocity: 0.75-1.2 m/s) and two fit descriptions of myelinated high- threshold(More)