Hartmut Fritzsche

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An electronic product catalogue (EPC) is a computer controlled information system with multimedia product presentations and navigation facilities. The paper presents the results of the EPK-x project for the systematic construction of EPCs. These include a software engineering process model, a high level speciication language for EPCs, and an integrated set(More)
A repertoire of various methods of computer sequence analysis was applied to phytochromes in order to gain new insights into their structure and function. A statistical analysis of 23 complete phytochrome sequences revealed regions of non-random amino acid composition, which are supposed to be of particular structural or functional importance. All(More)
The 24mer deoxyoligonucleotide 3'-d(T)10-5'-5'-d(C)4- d(A)10-3'(psC4) with an uncommon 5'-p-5'phosphodiester linkage was designed to enable the formation of a hairpin structure with unusual parallel-stranded stem. As reference hairpin structure with an antiparallel-stranded stem, the 24mer 5'-d(T)10-d(C)4-d(A)10-3'(apsC4) was chosen. The behaviour of these(More)
The infrared spectra of three different 25-mer parallel-stranded DNAs (ps-DNA) have been studied. We have used ps-DNAs containing either exclusively dA x dT base pairs or substitution with four dG x dC base pairs and have them compared with their antiparallel-stranded (aps) reference duplexes in a conventional B-DNA conformation. Significant differences(More)
The NMR structure analysis is described for two DNA molecules of identical stem sequences with a five base loop containing a pyrimidine, thymin or uracil, in between purines. These five unpaired nucleotides are bulged out and are known to induce a kink in the duplex structure. The dAATAA bulge DNA is kinked between the third and the fourth nucleotide. This(More)
An electronic product catalogue (EPC) is a computer controlled information system with multimedia product presentations and navigation facilities. The paper presents the results of the EPK-x project for the systematic construction of EPCs. These include a software engineering process model, a high level speciication language for EPCs, and an integrated set(More)
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