Harsh Kumar

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A case is reported of a 9-year old male who presented with abnormal behaviour and progressive diminution of vision. Pupils were middilated in both eyes but the pupillary reflexes were preserved. Fundus examination revealed a bilateral optic atrophy and radiological investigations showed a bilateral occipital calcification. We hereby document a case of(More)
A new series of isonicotinoyl hydrazone derivatives (3a–3o) have been synthesized, characterized and evaluated for in vitro antimycobacterial activity against M. tuberculosis H37Rv and two clinical isolates using tetrazolium microplate assay (TEMA). Some of these compounds showed moderate to good antimycobacterial activity at micro molar concentrations.(More)
As mobile devices evolve, end users have ever increasing demand for ubiquitous network access. WiFi, being now commonplace, has the potential to fulfill this demand. Apart from WiFi hotspots deployed by ISPs, home users start showing interest in sharing bandwidth with others (e.g. Fon bases its business model on users sharing open access points.) However,(More)
PURPOSE To analyze whether preinstillation of lignocaine potentiates mydriasis by tropicamide in dark eyes and to determine possible mechanisms for this effect. METHODS This investigation was conducted in two phases, the first being a double-masked, placebo-controlled, randomized clinical trial, enrolling 60 healthy dark brown eyes in 30 subjects aged 7(More)
BACKGROUND Prostate cancer is the most common cancer in men in many Western countries and is the second-leading cause of cancer in men. More than 30% of men over the age of 50 will develop a malignant change in the prostate. Common sites of metastasis include bone and regional lymph nodes. CASE REPORT This is a case report of prostate cancer in an elderly(More)
AIM The aim of this article is to present the usefulness of the nasolabial flap (NL flap) along with a detailed review of the factors that lead to its selection for the reconstruction of post-ablative oral floor defects. MATERIALS AND METHODS The records of patients who underwent the procedure between June 2009 and June 2011 were retrospectively analyzed.(More)
Enoyl–acyl carrier protein reductase (InhA) is an important enzyme for the biosynthesis of mycolic acids which are central constituents of the mycobacterium cell wall. In the present study, we synthesized, characterized hydrophobic N-acylated isonicotinic acid hydrazide derivatives (2a–2m) as potential enoyl–acyl carrier protein reductase (InhA) inhibitors(More)
In this study, N-(substituted phenyl)-2/4-(1H-indol-3-ylazo)-benzamides (1–26) were synthesized and screened for their in vitro antibacterial (Gram positive; S. aureus, B. subtilis and Gram negative; E. coli) and antifungal (C. albicans and A. niger) activities. The antimicrobial activity results indicated that compound,(More)