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EARLY ALL MICROBIOLOGIC assays for folic acid activity (FA) have used Streptococcus faecalis and Lactobacillus casei (1). Earlier it appeared that these organisms could not detect FA deficiency in man (2, 3); for example, in one study using S. faecalis there was no detectible activity in the fasting serum of humans (4). Administration of a loading dose of(More)
ANTOTHENIC ACID DEFICIENCY reduces biologic actylations and leads to a variety of pathologic changes in blood cholesterol partition and antibody production. Deficiency affects particularly the adrenal cortex, nervous system, the skin, and hair; it also affects longevity (1, 2, 3, 4). The ubiquity of pantothenic acid (as suggested by its name), makes it(More)