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Analysis of curing of a sustained release coating formulation by application of NIR spectroscopy to monitor changes physical-mechanical properties.
Analysis of curing of a sustained release coating formulation by application of NIR spectroscopy to monitor changes associated with glyceryl monostearate
- Harris Howland, R. Fahmy, S. Hoag
- Materials ScienceDrug development and industrial pharmacy
- 28 July 2015
Primary component analysis and parallel factor analysis showed that spectral changes could be could be directly related to the changes associated with the GMS during curing and partial least square models developed could predict the extent of curing and the final state of GMS post curing.
Pharmacokinetics and biodistribution of paclitaxel following intrauterine administration of PACLIMER® microspheres in female New Zealand rabbits
- S. K. Dordunoo, W. Vincek, Harris Howland, George Liu, Nobel Nemieboka, K. Bauer
- Medicine, Biology
- 15 April 2006
This study investigated the pharmacokinetics and bio-distribution of paclitaxel, an inhibitor of cell proliferation and angiogenesis, following intrauterine administration of PACLIMER® Microspheres in female New Zealand rabbits to optimize the therapy of cell proliferative and/or angiogenic-dependent uterine disorders.